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1

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

Steinthorsdottir, Valgerdur, Thorleifsson, Gudmar, Reynisdottir, Inga, Benediktsson, Rafn, Jonsdottir, Thorbjorg, Walters, G Bragi, Styrkarsdottir, Unnur, Gretarsdottir, Solveig, Emilsson, Valur, Ghos

Journal:

Nature Genetics

Year:

2007

Language:

english

File:

PDF, 1.41 MB

english, 2007

2

Author Correction: The rate of meiotic gene conversion varies by sex and age

Halldorsson, Bjarni V, Hardarson, Marteinn T, Kehr, Birte, Styrkarsdottir, Unnur, Gylfason, Arnaldur, Thorleifsson, Gudmar, Zink, Florian, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sulem, Patrick,

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 474 KB

english, 2018

3

Two Rare Mutations in the COL1A2 Gene Associate With Low Bone Mineral Density and Fractures in Iceland

Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Eiriksdottir, Berglind, Gudjonsson, Sigurjon A, Ingvarsson, Thorvaldur, Center, Jacqueline R, Nguyen, Tuan V, Eisman, John A, Christiansen, Claus, Thorstei

Journal:

Journal of Bone and Mineral Research

Year:

2016

Language:

english

File:

PDF, 206 KB

english, 2016

4

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

Styrkarsdottir, Unnur, Stefansson, Olafur A., Gunnarsdottir, Kristbjorg, Thorleifsson, Gudmar, Lund, Sigrun H., Stefansdottir, Lilja, Juliusson, Kristinn, Agustsdottir, Arna B., Zink, Florian, Halldor

Journal:

Nature Communications

Year:

2019

File:

PDF, 1.67 MB

2019

5

Publisher Correction: GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

Styrkarsdottir, Unnur, Stefansson, Olafur A., Gunnarsdottir, Kristbjorg, Thorleifsson, Gudmar, Lund, Sigrun H., Stefansdottir, Lilja, Juliusson, Kristinn, Agustsdottir, Arna B., Zink, Florian, Halldor

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 646 KB

english, 2019

6

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

Thorleifsson, Gudmar, Walters, G Bragi, Gudbjartsson, Daniel F, Steinthorsdottir, Valgerdur, Sulem, Patrick, Helgadottir, Anna, Styrkarsdottir, Unnur, Gretarsdottir, Solveig, Thorlacius, Steinunn, Jon

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 307 KB

english, 2008

7

Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene

Boer, Cindy Germaine, Yau, Michelle S, Rice, Sarah J, Coutinho de Almeida, Rodrigo, Cheung, Kathleen, Styrkarsdottir, Unnur, Southam, Lorraine, Broer, Linda, Wilkinson, Jeremy Mark, Uitterlinden, Andr

Journal:

Annals of the Rheumatic Diseases

Year:

2020

File:

PDF, 3.42 MB

2020

8

023 META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES OF OSTEOARTHRITIS

E. Evangelou, A.M. Valdes, U. Styrkársdóttir, H. Kerkhof, I. Jonsdottir, A. Uitterlinden, Y. Zhu, A. Cupples, J.P. Ioannidis, K. Stefanson, D. Felson, J. Van Meurs, T.D. Spector

Journal:

Osteoarthritis and Cartilage

Year:

2009

Language:

english

File:

PDF, 87 KB

english, 2009

9

Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density

Holm, Hilma, Edvardsson, Vidar, Walters, G Bragi, Styrkarsdottir, Unnur, Gudbjartsson, Daniel F, Sulem, Patrick, Halldorsson, Bjarni V, de Vegt, Femmie, d'Ancona, Frank C H, Thorleifsson, Gudmar

Journal:

Nature Genetics

Year:

2009

Language:

english

File:

PDF, 281 KB

english, 2009

10

355 GENOME-WIDE ASSOCIATION STUDY TO IDENTIFY NEW GENES AND PATHWAYS CONFERRING RISK TO OA SUSCEPTIBILITY IN MULTIPLE JOINT LOCATIONS AS DEFINED IN THE GARP STUDY

Y.F. Ramos, S.D. Bos, U. Styrkarsdottir, K. Panoutsopoulou, C. Keurentjes, N. Lakenberg, R. Nelissen, M. Kloppenburg, H. Kroon, A. Uitterlinden, J. Loughlin, E. Zeggini, I. Jonsdottir, J.B. van Meurs,

Journal:

Osteoarthritis and Cartilage

Year:

2011

Language:

english

File:

PDF, 64 KB

english, 2011

11

A Large-Scale Population-Based Analysis of Common Genetic Variation in the Thyroid Hormone Receptor Alpha Locus and Bone

Medici, Marco, Rivadeneira, Fernando, van der Deure, Wendy M., Hofman, Albert, van Meurs, Joyce B.J., Styrkársdottir, Unnur, van Duijn, Cornelia M., Spector, Timothy, Kiel on behalf of The GEFOS Conso

Journal:

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

12

Whole genome sequencing finds rare high-risk genotypes for hip osteoarthritis in the COMP and CHADL genes

Ingvarsson, T., Styrkarsdottir, U., Helgason, H., Sigudsson, A., Norddahl, G., Agustsdottir, A., Reynard, L., Garcia, A., Halldorsson, G., Jonasdottir, A., Magnusdottir, A., Oddson, A., Sulem, G., Zin

Journal:

Osteoarthritis and Cartilage

Year:

2017

Language:

english

File:

PDF, 269 KB

english, 2017

13

356 COMMON VARIANTS IN SKELETAL DYSPLASIA GENES ARE ASSOCIATED WITH OSTEOARTHRITIS

H. Kerkhof, O. Panagiotou, M. Irving, T. Esko, I. Meulenbelt, K. Panoutsopoulou, U. Styrkarsdottir, Y. Zhu, A. Cupples, D. Felson, M. Kloppenburg, N. Arden, H. Albert, E. Slagboom, L. Frank, A. Metspa

Journal:

Osteoarthritis and Cartilage

Year:

2011

Language:

english

File:

PDF, 307 KB

english, 2011

14

Functional conservation betweenSchizosaccharomyces pombe ste8andSaccharomyces cerevisiae STE11protein kinases in yeast signal transduction

Unnur Styrkársdóttir, Richard Egel, Olaf Nielsen

Journal:

Molecular Genetics and Genomics

Year:

1992

Language:

english

File:

PDF, 1.40 MB

english, 1992

15

Association analyses of 47,500 individuals identifies six fracture loci and 82 BMD loci clustering in biological pathways that regulate osteoblast and osteoclast activity

K. Estrada, E. Evangelou, Y.-H. Hsu, U. Styrkarsdottir, C.-T. Liu, A. Moayyeri, S. Kaptoge, E. Duncan, N. Amin, D. Kiel, D. Karasik, O.M. Albagha, M. Brown, T.D. Spector, M.C. Zillikens, C. Ohlsson, G

Journal:

Year:

2011

Language:

english

File:

PDF, 125 KB

english, 2011

16

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

Evangelou, E., Kerkhof, H. J., Styrkarsdottir, U., Ntzani, E. E., Bos, S. D., Esko, T., Evans, D. S., Metrustry, S., Panoutsopoulou, K., Ramos, Y. F. M., Thorleifsson, G., Tsilidis, K. K., Arden, N.,

Journal:

Annals of the Rheumatic Diseases

Year:

2014

Language:

english

File:

PDF, 696 KB

english, 2014

17

Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis

Styrkarsdottir, Unnur, Helgason, Hannes, Sigurdsson, Asgeir, Norddahl, Gudmundur L, Agustsdottir, Arna B, Reynard, Louise N, Villalvilla, Amanda, Halldorsson, Gisli H, Jonasdottir, Aslaug, Magnusdotti

Journal:

Nature Genetics

Year:

2017

Language:

english

File:

PDF, 657 KB

english, 2017

18

Twenty loci associated with bone mineral density identified by large-scale meta-analysis of genome-wide association datasets

F. Rivadeneira, U. Styrkarsdottir, K. Estrada, B. Halldorsson, Y. Hsu, J.B. Richards, M.C. Zillikens, F. Kavvoura, N. Amin, Y. Aulchenko, L. Cupples, P. Deloukas, S. Demissie, E. Grundberg, A. Hofman,

Journal:

Year:

2009

Language:

english

File:

PDF, 67 KB

english, 2009

19

Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke

Solveig Gretarsdottir, Gudmar Thorleifsson, Andrei Manolescu, Unnur Styrkarsdottir, Anna Helgadottir, Andreas Gschwendtner, Konstantinos Kostulas, Gregor Kuhlenbäumer, Steve Bevan, Thorbjorg Jonsdotti

Journal:

Annals of Neurology

Year:

2008

Language:

english

File:

PDF, 91 KB

english, 2008

20

Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures

Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Gudjonsson, Sigurjon A., Sigurdsson, Asgeir, Center, Jacqueline R., Lee, Seung Hun, Nguyen, Tuan V., Kwok, Timothy C.Y., Lee, Jenny S.W., Ho, Suzanne C., W

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 967 KB

english, 2016

21

Thesmt-0mutation which abolishes mating-type switching in fission yeast is a deletion

Unnur Styrkársdóttir, Richard Egel, Olaf Nielsen

Journal:

Current Genetics

Year:

1993

Language:

english

File:

PDF, 303 KB

english, 1993

22

Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density

Ivarsdottir, Erna V., Benonisdottir, Stefania, Thorleifsson, Gudmar, Sulem, Patrick, Oddsson, Asmundur, Styrkarsdottir, Unnur, Kristmundsdottir, Snaedis, Arnadottir, Gudny A., Thorgeirsson, Gudmundur,

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 1.18 MB

english, 2019

23

New sequence variants associated with bone mineral density

Styrkarsdottir, Unnur, Halldorsson, Bjarni V, Gretarsdottir, Solveig, Gudbjartsson, Daniel F, Walters, G Bragi, Ingvarsson, Thorvaldur, Jonsdottir, Thorbjorg, Saemundsdottir, Jona, Snorradóttir, Stein

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 243 KB

english, 2008

24

Multiple Genetic Loci for Bone Mineral Density and Fractures

Styrkarsdottir, Unnur, Halldorsson, Bjarni V., Gretarsdottir, Solveig, Gudbjartsson, Daniel F., Walters, G. Bragi, Ingvarsson, Thorvaldur, Jonsdottir, Thorbjorg, Saemundsdottir, Jona, Center, Jacqueli

Journal:

Boston Medical and Surgical Journal

Year:

2008

Language:

english

File:

PDF, 793 KB

english, 2008

25

Corrigendum: Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis

Styrkarsdottir, Unnur, Helgason, Hannes, Sigurdsson, Asgeir, Norddahl, Gudmundur L, Agustsdottir, Arna B, Reynard, Louise N, Villalvilla, Amanda, Halldorsson, Gisli H, Jonasdottir, Aslaug, Magnusdotti

Journal:

Nature Genetics

Year:

2017

File:

PDF, 55 KB

2017

26

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

Estrada, Karol, Styrkarsdottir, Unnur, Evangelou, Evangelos, Hsu, Yi-Hsiang, Duncan, Emma L, Ntzani, Evangelia E, Oei, Ling, Albagha, Omar M E, Amin, Najaf, Kemp, John P, Koller, Daniel L, Li, Guo, Li

Journal:

Nature Genetics

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

27

Linkage of Osteoporosis to Chromosome 20p12 and Association to BMP2

Styrkarsdottir, Unnur, Cazier, Jean-Baptiste, Kong, Augustine, Rolfsson, Ottar, Larsen, Helene, Bjarnadottir, Emma, Johannsdottir, Vala D, Sigurdardottir, Margret S, Bagger, Yu, Christiansen, Claus, R

Journal:

Year:

2003

Language:

english

File:

PDF, 427 KB

english, 2003

28

A systematic evaluation of 151 candidate genes for their association with osteoporosis and osteoporotic fracture in a meta-analysis of genome-wide association data

J. Richards, F.K. Kavvoura, F. Rivadeneira, U. Styrkarsdottir, K. Estrada, B. Halldorsson, Y. Hsu, M. Zillikens, S.G. Wilson, B. Mullins, N. Amin, Y.A. Aulchenko, L. Cupples, P. Deloukas, S. Demissie,

Journal:

Year:

2009

Language:

english

File:

PDF, 68 KB

english, 2009

29

Osteoarthritis genetics and genomics: Status and future perspectives

Styrkarsdottir, U.

Journal:

Osteoarthritis and Cartilage

Year:

2015

Language:

english

File:

PDF, 43 KB

english, 2015

30

Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis

Styrkarsdottir, Unnur, Lund, Sigrun H., Thorleifsson, Gudmar, Zink, Florian, Stefansson, Olafur A., Sigurdsson, Jon K., Juliusson, Kristinn, Bjarnadottir, Kristbjörg, Sigurbjornsdottir, Sara, Jonsson,

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 1.48 MB

english, 2018

31

Variants in DENND1A Are Associated with Polycystic Ovary Syndrome in Women of European Ancestry

Welt, Corrine K., Styrkarsdottir, Unnur, Ehrmann, David A., Thorleifsson, Gudmar, Arason, Gudmundur, Gudmundsson, Jens A., Ober, Carole, Rosenfield, Robert L., Saxena, Richa, Thorsteinsdottir, Unnur,

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2012

Language:

english

File:

PDF, 134 KB

english, 2012

32

Genome-Wide Meta-Analysis for Serum Calcium Identifies Significantly Associated SNPs near the Calcium-Sensing Receptor (CASR) Gene

Kapur, Karen, Johnson, Toby, Beckmann, Noam D., Sehmi, Joban, Tanaka, Toshiko, Kutalik, Zoltán, Styrkarsdottir, Unnur, Zhang, Weihua, Marek, Diana, Gudbjartsson, Daniel F., Milaneschi, Yuri, Holm, Hil

Journal:

Year:

2010

Language:

english

File:

PDF, 422 KB

english, 2010

33

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus

Oei, L., Hsu, Y.-H., Styrkarsdottir, U., Eussen, B. H., de Klein, A., Peters, M. J., Halldorsson, B., Liu, C.-T., Alonso, N., Kaptoge, S. K., Thorleifsson, G., Hallmans, G., Hocking, L. J., Husted, L.

Journal:

Journal of Medical Genetics

Year:

2014

Language:

english

File:

PDF, 837 KB

english, 2014

34

Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome

Day, Felix R., Hinds, David A., Tung, Joyce Y., Stolk, Lisette, Styrkarsdottir, Unnur, Saxena, Richa, Bjonnes, Andrew, Broer, Linda, Dunger, David B., Halldorsson, Bjarni V., Lawlor, Debbie A., Laval,

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 409 KB

english, 2015

35

The rate of meiotic gene conversion varies by sex and age

Halldorsson, Bjarni V, Hardarson, Marteinn T, Kehr, Birte, Styrkarsdottir, Unnur, Gylfason, Arnaldur, Thorleifsson, Gudmar, Zink, Florian, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sulem, Patrick,

Journal:

Nature Genetics

Year:

2016

Language:

english

File:

PDF, 717 KB

english, 2016

36

Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus

Hackinger, Sophie, Trajanoska, Katerina, Styrkarsdottir, Unnur, Zengini, Eleni, Steinberg, Julia, Ritchie, Graham R.S., Hatzikotoulas, Konstantinos, Gilly, Arthur, Evangelou, Evangelos, Kemp, John P.,

Journal:

Human Molecular Genetics

Year:

2017

Language:

english

File:

PDF, 264 KB

english, 2017

37

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

Rivadeneira, Fernando, Styrkársdottir, Unnur, Estrada, Karol, Halldórsson, Bjarni V, Hsu, Yi-Hsiang, Richards, J Brent, Zillikens, M Carola, Kavvoura, Fotini K, Amin, Najaf, Aulchenko, Yurii S

Journal:

Nature Genetics

Year:

2009

Language:

english

File:

PDF, 723 KB

english, 2009

38

Variants in the LRP5 gene influence BMD both through common variants of small effect and rare mutations of large effect in osteoporotic families

G. Sigurdsson, U. Styrkarsdottir, B.V. Halldorsson, K. Stefansson

Journal:

Year:

2009

Language:

english

File:

PDF, 67 KB

english, 2009

39

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

Evangelou, E., Valdes, A. M., Kerkhof, H. J. M., Styrkarsdottir, U., Zhu, Y., Meulenbelt, I., Lories, R. J., Karassa, F. B., Tylzanowski, P., Bos, S. D., Akune, T., Arden, N. K., Carr, A., Chapman, K.

Journal:

Annals of the Rheumatic Diseases

Year:

2011

Language:

english

File:

PDF, 354 KB

english, 2011

40

Sequence variant at 8q24.21 associates with sciatica caused by lumbar disc herniation

Bjornsdottir, Gyda, Benonisdottir, Stefania, Sveinbjornsson, Gardar, Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Walters, G. Bragi, Bjornsson, Aron, Olafsson, Ingvar H., Ulfarsson, Elfar, Vikingsson,

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 550 KB

english, 2017

41

Identification of five novel osteoarthritis susceptibility loci through the UK biobank resourse of five novel osteoarthritis susceptibility loci through the UK biobank resourse

Zengini, E., Hatzikotoulas, K., Tachmazidou, I., Hackinger, S., Styrkarsdottir, U., Suveges, D., Killian, B., Gilly, A., Ingvarsson, T., Jonsson, H., Babis, G., Thorsteinsdottir, U., Stefansson, K., W

Journal:

Osteoarthritis and Cartilage

Year:

2017

Language:

english

File:

PDF, 130 KB

english, 2017

42

A genome-wide association study identifies a common variant near the GRP22 gene as a new locus involved in prevalence and progression of osteoarthritis

H.J.M. Kerkhof, I. Jonsdottir, I. Meulenbelt, L. Stolk, A.M. Valdes, G. Zhai, Y. Zhu, M. Doherty, S. Doherty, A. Tsezou, A. Gonzalez, A. Carr, D.T. Felson, U. Styrkarsdottir, E.P. Slagboom, J. Loughli

Journal:

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

43

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

Styrkarsdottir, Unnur, Stefansson, Olafur A., Gunnarsdottir, Kristbjorg, Thorleifsson, Gudmar, Lund, Sigrun H., Stefansdottir, Lilja, Juliusson, Kristinn, Agustsdottir, Arna B., Zink, Florian, Halldor

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 1.67 MB

english, 2019

44

Impact of Genetics on Low Bone Mass in Adults

Gunnar Sigurdsson, Bjarni V Halldorsson, Unnur Styrkarsdottir, Kristleifur Kristjansson, Kari Stefansson

Journal:

Journal of Bone and Mineral Research

Year:

2008

Language:

english

File:

PDF, 238 KB

english, 2008

45

Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Sulem, Patrick, Gudbjartsson, Daniel F., Sigurdsson, Asgeir, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Oddsson, Asmundur, Helgason, Agnar, Magnusson, Ol

Journal:

Year:

2013

Language:

english

File:

PDF, 190 KB

english, 2013

46

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31

Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Helgadottir, Hafdis T, Bomer, Nils, Metrustry, Sarah, Bierma-Zeinstra, S, Strijbosch, Annelieke M, Evangelou, Evangelos, Hart, Deborah, Beekman, Marian, Jo

Journal:

Nature Genetics

Year:

2014

Language:

english

File:

PDF, 522 KB

english, 2014

47

A common biological basis of obesity and nicotine addiction

Thorgeirsson, T E, Gudbjartsson, D F, Sulem, P, Besenbacher, S, Styrkarsdottir, U, Thorleifsson, G, Walters, G B, Furberg, H, Sullivan, P F, Marchini, J, McCarthy, M I, Steinthorsdottir, V, Thorsteins

Journal:

Translational Psychiatry

Year:

2013

Language:

english

File:

PDF, 385 KB

english, 2013

48

Two-step activation of meiosis by the mat1 locus in Schizosaccharomyces pombe.

Willer, M, Hoffmann, L, Styrkársdóttir, U, Egel, R, Davey, J, Nielsen, O

Journal:

Molecular and Cellular Biology

Year:

1995

Language:

english

File:

PDF, 675 KB

english, 1995

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